At the 68th International Association for Dental Research, Japan (JADR) General Assembly / Academic Conference held online from November 7-8, 2020, Durga Paudel, a graduate student from Department of Oral Medicine and Pathology, Graduate School of Dentistry, of our university, was selected as a final candidate of JADR for IADR Hatton Awards 2021. He will represent Japan to compete with the finalists from all over the world at the 99th International Association for Dental Research (IADR), General Session (Boston, USA). The event is hosted by IADR, the world's largest international and interdisciplinary dentistry society.

Title: Proteomics and Metagenomics of Saliva in Psychological Stress.
Presenters: D. PAUDEL, Y. KURAMITSU, O. UEHARA, T. MORIKAWA, K. YOSHIDA, Y. ABIKO.

This study shows the effect of psychological stress on salivary proteins and oral bacteria. In the saliva of rats subjected to chronic psychological stress, changes were observed in the expression of proteins that induce oral candidiasis and regulate bitter taste sensation. The study also suggests that the changes in the oral bacteria due to psychological stress may cause chronic inflammation of oral mucosa. These findings are thought to contribute to the understanding of pathophysiology of oral mucosal diseases and psychosomatic dental disorders, where psychological stress is involved in the onset and exacerbation of these diseases.



With this award, we are the first university in the field of clinical oral pathology to receive all three awards sponsored by JADR.
• JADR / Joseph Lister Award: Fumiya Harada (2012)
• JADR / GC Young Investigator Award: KokiYoshida (2018)
• IADR Hatton Awards candidate (JADR final candidate): Durga Paudel (2020)