1.Constitutive expression of hypoxia-inducible factor-1α renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation

N Akakura, M Kobayashi, I Horiuchi, A Suzuki, J Wang… - Cancer research, 2001 - AACR


引用回数:409

膵がん細胞でHIF-1の発現が亢進していることを世界で初めて報告した論文。


2.Dominant-negative hypoxia-inducible factor-1α reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism

…, T Sugiyama, M Hosokawa, M Kobayashi - The American journal of …, 2003 - Elsevier


引用回数:214

膵がん細胞でHIF-1発現を阻害すると膵がん細胞の造腫瘍性が失われることを報告した論文。


3.Hypoxia induces adhesion molecules on cancer cells: a missing link between Warburg effect and induction of selectin-ligand carbohydrates

…, J Chen, M Kobayashi, M Hosokawa… - Proceedings of the …, 2004 - National Acad Sciences


引用回数:178

低酸素環境下でセレクチンのligand発現が亢進しててん異能が上昇することを報告した論文。


4.Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells

H Niizeki, M Kobayashi, I Horiuchi, N Akakura… - British journal of …, 2002 - nature.com


引用回数:94

低酸素環境下でAMFが産生されて膵がん細胞の転移能が上昇することを報告した論文。


5.Acetylcholine from vagal stimulation protects cardiomyocytes against ischemia and hypoxia involving additive non-hypoxic induction of HIF-1α

…, M Kuwabara, RG Katare, K Okudela, M Kobayashi… - FEBS letters, 2005 - Elsevier


引用回数:120


6.Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia

…, T Kondo, M Asaka, F Okada, M Kobayashi - Experimental cell …, 2007 - Elsevier


引用回数:63


7.Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation

J Chen, M Kobayashi, S Darmanin, Y Qiao… - The American journal of …, 2009 - Elsevier


引用回数:80


8.MyD88 is involved in the signalling pathway for Taxol‐induced apoptosis and TNF‐α expression in human myelomonocytic cells

J Wang, M Kobayashi, M Han, S Choi… - British journal of …, 2002 - Wiley Online Library


引用回数:62


9.Selective secretion of chemoattractants for haemopoietic progenitor cells by bone marrow endothelial cells: a possible role in homing of haemopoietic …

K Imai, M Kobayashi, J Wang… - British journal of …, 1999 - Wiley Online Library


引用回数:138

造血幹細胞の骨髄定着に骨髄血管内皮細胞が分泌するケモカインが関与することを世界で初めて報告した論文。


10.Selective transendothelial migration of hematopoietic progenitor cells: a role in homing of progenitor cells

K Imai, M Kobayashi, J Wang, Y Ohiro… - …, 1999 - bloodjournal.hematologylibrary.org


引用回数:110

造血幹細胞の骨髄定着に骨髄血管内皮細胞を通り抜ける能力が関与することを報告した論文。


他130編以上